December 13, 2017
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Home >> Newsletter >> Fibromax Test عربي

Fibro-Max

(Super Biomarker)

 

 

The goal of Saridar Lab is the development of non - invasive diagnostic tests which aim to improve the management of liver disease and that can achieve a 50% reduction in number of required liver biopsies.

 

Fibro-Max is actually five tests all in one:

 

1) Fibro Test

 

Non invasive alternative to measure fibrosis in patients with chronic hepatitis C or B, alcoholic liver disease and metabolic steatosis:

 

F0 : No Fibrosis

F1 : Portal Fibrosis

F2 : Bridging Fibrosis with Few Septa

F3 : Bridging Fibrosis with Many Septa

F4 : Cirrhosis

 

2) Acti Test

 

The Acti Test offers a non invasive alternative to measure necro-inflammatory activity in patients with chronic hepatitis C or B:

 

A0 : No activity

A1 : Minimal Activity

A2 : Moderate Activity

A3 : Severe Activity

 

3) Steato Test

 

The Steato Test offers a non invasive alternative to measure hepatic steatosis (triglyceride deposits in the liver) in patients with chronic hepatitis C or B, alcoholic liver disease and metabolic steatosis (overweight, diabetes, hyperlipidemia):

 

S0: No steatosis

S1: Minimal steatosis, less than 5% of hepatocytes with steatosis

S2: Moderate steatosis, between 6-32% of hepatocytes with steatosis

S3: Severe steatosis, between 33-100% of hepatocytes with steatosis

 

4) Nash Test

 

The Nash Test offers a non invasive alternative to diagnose non alcoholic steato hepatitis (NASH) in patients with metabolic steatosis (overweight, diabetes and hyperlipidemia):

 

N0 : No Nash

N1 : Borderline

N2 : Nash

 

 5) Ash Test

 

The Ash Test offers a non invasive alternative to measure alcoholic steato hepatitis (ASH) in patients with alcoholic liver disease:

 

H0 : No Ash

H1 : Minimal Ash

H2 : Moderate Ash

H3 : Severe Ash

 

What are the most frequent causes of false positive results for Fibro test & Acti Test?

 

·  Haemolysis, which decreases haptoglobin as observed with ribavirin treatment, or cardiac prosthesis.

·  Gilbert syndrome, which increases total bilirubin.

·  Extra-hepatic cholestasis, which increases GGT and total bilirubin.

·  Drugs which increase total bilirubin as atazanavir.

 


 
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